I can think of a few ways to do it. It all depends on how large your hollow bead is, and how wide the holes are. You can plug one hole with something--string one of those tiny corks on thread or wire and run that through the bead, or perhaps a dot of superglue with a small spacer to cover would do it if the hole isn't too big. I've seen pictures of large hollows filled up with seed beads for a gumball-machine effect, and once a large clear one filled with tiny snail shells. In both cases, small-holed spacers were used to block up the bottom hole. For hair or sand or other really tiny things, you'd need a glue seal. These were pendant beads, with the holes positioned vertically. For horizontally-oriented beads, like in a necklace or bracelet, large fillers could be blocked in by small-holed spacers as well, but sand-filled beads would have to be sealed. Also, use a glue that's got some flex to it. Anything that dries rigid will eventually snap off of the bead. Good luck!
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